Despite the considerable progress already achieved, implants still have a limited lifespan in the body and failures are rather frequent. It is widely accepted that further improvement in biomaterials can only be achieved by endowing them with higher surface functionality. Very recently the applicants showed that by treating Ti and Si with a femtosecond laser complex bimodal distribution surface topographies with extremely promising characteristics for biomedical applications.
The aim of the present work is to explore ultrafast lasers as a tool to enhance the interfacial behaviour of skeletal reconstruction materials. The work programme includes a detailed study of the texture, structure, and properties of laser treated surfaces in a wide range of materials with covalent, ionic, and metallic bonding. The treated surfaces will be analysed by profilometry, FEG-SEM/EDS/EBSD, glancing incidence X-Ray diffraction, ATR-FTIR spectroscopy, microRaman spectroscopy, AFM, XPS and Auger electron spectroscopy. The most promising materials will be submitted to detailed in vitro biological testing using human osteoblast cell cultures.
IST - LSF, (Laser Surface Functionalisation Lab, Lisbon)
UB1 - CBMN (Chimie et Biologie des Membranes et des Nanoobjets, Bordeaux)